Intersections (1985–2005) is a 4-CD and DVD retrospective boxed set by Bruce Hornsby. The tracks are a mixture of previously unreleased live recordings, unreleased studio recordings, and album cuts. The boxed set's title emphasizes the large number of musical collaborations Hornsby has embarked upon during his career, as evidenced by the list of collaborators below.

The discs are thematically broken into three categories: "Top 90 Time", "Solo Piano, Tribute Records, Country-Bluegrass, Movie Scores," and "By Request (Favorites and Best Songs)" (two CDs). A full third of the music is previously unreleased; many familiar tracks are presented as unreleased live versions rather than the original studio recordings, and the majority of the remaining tracks are from single b-sides, collaborations and/or tribute albums and movie soundtracks.

Some noteworthy collaborations include a piano-and-saxophone duet with Ornette Coleman and a performance with Roger Waters of Pink Floyd's "Comfortably Numb." The set also offers a number of excellent examples of Hornsby's re-inventiveness with his own compositions, particularly in a live setting, for instance three different versions of “The Valley Road” are included—a live "bluesy funk" version with the Noise Makers, a Grammy-winning bluegrass version with the Nitty Gritty Dirt Band, and "a loose and sloppy but totally grooving boogie" take with the Grateful Dead. Critics have said that Hornsby's particular integrations of different musical genres, and his passion for reinventing his own compositions, create a kind of music many might "never hear" otherwise as it is "a kind of music no one else is making."

"Song H" was a new composition that was nominated for Best Pop Instrumental at the 2007 Grammy Awards.